Title : Histone deacetylase inhibitor trichostatin A induces cell-cycle arrest/apoptosis and hepatocyte differentiation in human hepatoma cells.

Pub. Date : 2003 Feb 20

PMID : 12494463






3 Functional Relationships(s)
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1 We analyzed the effects of TSA, a specific and potent HDAC inhibitor, on the human hepatoma cell lines HepG2 and Huh-7. trichostatin A MIR7-3 host gene Homo sapiens
2 TSA increased levels of acetylated histones H3 and H4 in both HepG2 and Huh-7. trichostatin A MIR7-3 host gene Homo sapiens
3 TSA upregulated the ammonia removal rate and the albumin synthesis rate of HepG2 and Huh-7. trichostatin A MIR7-3 host gene Homo sapiens