Title : The metabolism of clopidogrel is catalyzed by human cytochrome P450 3A and is inhibited by atorvastatin.

Pub. Date : 2003 Jan

PMID : 12485953






1 Functional Relationships(s)
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1 Microsomes prepared from dexamethasone-pretreated rats metabolized clopidogrel at a rate of 3.8 nmol min(-1) nmol of p450(-1), which is 65 and 1270% faster than the rate of metabolism by microsomes from control and beta-napthoflavone-treated rats, respectively. beta-napthoflavone cytochrome P450 family 2 subfamily B member 6 Homo sapiens