Title : The guanine nucleotide exchange factor trio activates the phagocyte NADPH oxidase in the absence of GDP to GTP exchange on Rac. "The emperor's nw clothes".

Pub. Date : 2003 Feb 14

PMID : 12475976






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The superoxide-generating NADPH oxidase complex of phagocytes consists of a membrane-associated flavocytochrome b(559) and four cytosolic components as follows: p47(phox), p67(phox), p40(phox), and the small GTPase Rac (1 or 2). Superoxides AKT serine/threonine kinase 1 Homo sapiens