Title : Delayed induction of delta-6 and delta-5 desaturases by a peroxisome proliferator.

Pub. Date : 2002 Dec 20

PMID : 12470654






3 Functional Relationships(s)
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1 This response of D6D is paradoxical because SREBP-1c transactivates genes for fatty acid synthesis in liver, while PP induce enzymes for fatty acid oxidation. Fatty Acids fatty acid desaturase 2 Rattus norvegicus
2 This response of D6D is paradoxical because SREBP-1c transactivates genes for fatty acid synthesis in liver, while PP induce enzymes for fatty acid oxidation. Fatty Acids fatty acid desaturase 2 Rattus norvegicus
3 We hypothesized that the induction of D6D gene by PP is a compensatory response to the increased HUFA demand caused by peroxisome proliferation and induction of fatty acid oxidation. Fatty Acids fatty acid desaturase 2 Rattus norvegicus