Title : Kinetically controlled optical resolution of racemic norbornene aldehyde derivatives.

Pub. Date : 2003 Jan

PMID : 12467044






1 Functional Relationships(s)
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1 The reaction of a diastereomeric mixture of the ene acetals 2 and 2", derived from racemic norbornene aldehydes (+/-)-1 and chiral nonracemic (S,S)-hydrobenzoin 7, with NBS (0.5-0.6 eq.) in the presence of H(2)O proceeded in a kinetically controlled manner to give the optically pure hydroxy aldehydes 3 along with the intact ene acetals 2". Water nibrin Homo sapiens