Title : Nitric oxide co-ordinates the activities of the capacitative and non-capacitative Ca2+-entry pathways regulated by vasopressin.

Pub. Date : 2003 Mar 1

PMID : 12459038






4 Functional Relationships(s)
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1 In A7r5 vascular smooth muscle cells vasopressin, via arachidonic acid, regulates two Ca(2+)-entry pathways. Arachidonic Acid arginine vasopressin Rattus norvegicus
2 Inhibition of CCE by vasopressin requires NOS III and the requirement lies downstream of arachidonic acid. Arachidonic Acid arginine vasopressin Rattus norvegicus
3 Stimulation of NCCE by vasopressin also requires NOS III, but the stimulation is neither mimicked by cGMP nor blocked by inhibitors of soluble guanylate cyclase or protein kinase G. We conclude that arachidonic acid formed in response to vasopressin stimulates NOS III. Arachidonic Acid arginine vasopressin Rattus norvegicus
4 Stimulation of NCCE by vasopressin also requires NOS III, but the stimulation is neither mimicked by cGMP nor blocked by inhibitors of soluble guanylate cyclase or protein kinase G. We conclude that arachidonic acid formed in response to vasopressin stimulates NOS III. Arachidonic Acid arginine vasopressin Rattus norvegicus