Title : Synthesis and structure-activity relationships of novel 7-substituted 1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acids as antitumor agents. Part 1.

Pub. Date : 2002 Dec 5

PMID : 12459024






1 Functional Relationships(s)
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1 (3) At the C-7 position, aminopyrrolidine derivatives are more effective than other amines or thioether derivatives. Sulfides complement C7 Homo sapiens