Title : A spatial focusing model for G protein signals. Regulator of G protein signaling (RGS) protien-mediated kinetic scaffolding.

Pub. Date : 2003 Feb 28

PMID : 12446706






2 Functional Relationships(s)
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1 Evidence supporting this model includes a GTP-dependent enhancement of guanosine 5"-3-O-(thio)triphosphate (GTPgammaS) binding to G(i) by RGS. Guanosine Triphosphate paired like homeodomain 2 Homo sapiens
2 Furthermore, a kinetic model including only the GAP activity of RGS replicates the GTP-dependent enhancement of GTPgammaS binding observed experimentally. Guanosine Triphosphate paired like homeodomain 2 Homo sapiens