Title : Analysis of the pi-pi stacking interactions between the aminoglycoside antibiotic kinase APH(3')-IIIa and its nucleotide ligands.

Pub. Date : 2002 Nov

PMID : 12445771






1 Functional Relationships(s)
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1 A key contact in the active site of an aminoglycoside phosphotransferase enzyme (APH(3")-IIIa) is a pi-pi stacking interaction between Tyr42 and the adenine ring of bound nucleotides. Adenine acylaminoacyl-peptide hydrolase Homo sapiens