Title : Rhynchophylline and isorhynchophylline inhibit NMDA receptors expressed in Xenopus oocytes.

Pub. Date : 2002 Nov 22

PMID : 12433591






1 Functional Relationships(s)
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1 Rhynchophylline and isorhynchophylline (30 microM) significantly reduced the maximal current responses evoked by NMDA and glycine (a co-agonist of NMDA receptor), but had no effect on the EC(50) values and Hill coefficients of NMDA and glycine for inducing currents. Glycine glutamate ionotropic receptor NMDA type subunit 1 L homeolog Xenopus laevis