Title : Preparation of anfi-CD3 and anti-IgM&mgr; chain bispecific antibody by cell fusion.

Pub. Date : 2001

PMID : 12426160






1 Functional Relationships(s)
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1 METHODS: Mouse hybridoma cell line secreting anti-human CD3 monoclonal antibody (mAb) was trans formed into HAT-sensitive cells by 8-azaguanine, which was subsequently transfected by plasmid pCDaA3 containing neoR marker gene via FuGENETM6. Azaguanine CD3 antigen, epsilon polypeptide Mus musculus