Title : Unexpected down-regulation of the hIK1 Ca2+-activated K+ channel by its opener 1-ethyl-2-benzimidazolinone in HaCaT keratinocytes. Inverse effects on cell growth and proliferation.

Pub. Date : 2003 Jan 31

PMID : 12421833






3 Functional Relationships(s)
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1 Unexpected down-regulation of the hIK1 Ca2+-activated K+ channel by its opener 1-ethyl-2-benzimidazolinone in HaCaT keratinocytes. 1-ethyl-2-benzimidazolinone potassium calcium-activated channel subfamily N member 4 Homo sapiens
2 When we incubated cells with the hIK1 opener, 1-ethyl-2-benzimidazolinone (1-EBIO), to investigate the cellular consequences of prolonged channel activity, an unexpected down-regulation of channels occurred within a few hours. 1-ethyl-2-benzimidazolinone potassium calcium-activated channel subfamily N member 4 Homo sapiens
3 When we incubated cells with the hIK1 opener, 1-ethyl-2-benzimidazolinone (1-EBIO), to investigate the cellular consequences of prolonged channel activity, an unexpected down-regulation of channels occurred within a few hours. 1-ethyl-2-benzimidazolinone potassium calcium-activated channel subfamily N member 4 Homo sapiens