Title : Cyclooxygenase-2 overexpression reduces apoptotic susceptibility by inhibiting the cytochrome c-dependent apoptotic pathway in human colon cancer cells.

Pub. Date : 2002 Nov 1

PMID : 12414664






1 Functional Relationships(s)
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1 NSAIDs and 5-FU induced the mitochondrial release of cytochrome c as well as caspase-3 and -9 activation, and to a much lesser extent, caspase-8. Fluorouracil caspase 3 Homo sapiens