Title : Restoration of ethanol-compromised T(h)1 responses by sodium orthovanadate.

Pub. Date : 2002 Nov

PMID : 12407014






2 Functional Relationships(s)
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1 In the present report we explore the use of the phosphatase inhibitor, Na3 VO4 to restore IFN-gamma secretion in the presence of ethanol both in vivo and in vitro. Ethanol interferon gamma Mus musculus
2 Our data support the contention that ethanol, by up-regulating phosphotyrosine phosphatase, diminishes the IFN-gamma signal transduction pathway. Ethanol interferon gamma Mus musculus