Title : Altered adrenal gland cholesterol metabolism in the apoE-deficient mouse.

Pub. Date : 2002 Nov

PMID : 12401891






2 Functional Relationships(s)
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1 Previous studies suggest the hypothesis that apoE produced by adrenocortical cells modulates cellular cholesterol metabolism to enhance the storage of esterified cholesterol (EC) at the expense of cholesterol delivery to the steroidogenic pathway. Cholesterol Esters apolipoprotein E Mus musculus
2 Adrenal gland EC content and the EC/free cholesterol (FC) ratio in mice stressed by adrenocorticotropin (ACTH) treatment or saline injection were reduced in apoe(-/-) compared to apoe(+/+) mice. Cholesterol Esters apolipoprotein E Mus musculus