Pub. Date : 2003 Jan 1
PMID : 12393431
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Expression of kinase-deficient Syk or pretreatment with piceatannol markedly suppressed IL-2-stimulated activation of PI 3-kinase and Akt, demonstrating that Syk is upstream of PI 3-kinase and Akt. | 3,3',4,5'-tetrahydroxystilbene | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Expression of kinase-deficient Syk or pretreatment with piceatannol markedly suppressed IL-2-stimulated activation of PI 3-kinase and Akt, demonstrating that Syk is upstream of PI 3-kinase and Akt. | 3,3',4,5'-tetrahydroxystilbene | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | However, constitutively active PI 3-kinase reversed this loss of Akt function caused by kinase-deficient Syk or piceatannol. | 3,3',4,5'-tetrahydroxystilbene | AKT serine/threonine kinase 1 | Homo sapiens |