Title : Coupling of c-Src to large conductance voltage- and Ca2+-activated K+ channels as a new mechanism of agonist-induced vasoconstriction.

Pub. Date : 2002 Oct 29

PMID : 12391293






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Iberiotoxin, a MaxiK blocker, antagonizes the relaxation induced by Lavendustin A or PP2, indicating that c-Src inhibits the Iberiotoxin-sensitive component, likely MaxiK channels. lavendustin A potassium calcium-activated channel subfamily M alpha 1 Homo sapiens
2 Iberiotoxin, a MaxiK blocker, antagonizes the relaxation induced by Lavendustin A or PP2, indicating that c-Src inhibits the Iberiotoxin-sensitive component, likely MaxiK channels. lavendustin A potassium calcium-activated channel subfamily M alpha 1 Homo sapiens
3 In agreement, coronary muscle MaxiK currents were enhanced by Lavendustin A. lavendustin A potassium calcium-activated channel subfamily M alpha 1 Homo sapiens