Title : Inhibition of human chorionic gonadotropin beta-subunit modulates the mitogenic effect of c-myc in human prostate cancer cells.

Pub. Date : 2002 Nov 1

PMID : 12386920






2 Functional Relationships(s)
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1 The purpose of this study was to test the hypothesis that effective growth inhibition in the refractory cancer cells can be achieved by blocking c-myc along with a growth factor using a novel phosphorodiamidate morpholino antisense oligomer-based approach. phosphorodiamidate morpholino MYC proto-oncogene, bHLH transcription factor Homo sapiens
2 RESULTS: Antisense phosphorodiamidate morpholino oligomers directed against beta-hCG and c-myc caused a specific decrease of the target protein levels. phosphorodiamidate morpholino MYC proto-oncogene, bHLH transcription factor Homo sapiens