Title : Cooperative nucleotide binding to the human erythrocyte sugar transporter.

Pub. Date : 2002 Oct 22

PMID : 12379106






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 When complexed with cytosolic ATP, GluT1 exhibits increased affinity for the sugar export site ligand cytochalasin B, prolonged substrate occlusion, reduced net sugar import capacity, and diminished reactivity with carboxyl terminal peptide-directed antibodies. Sugars solute carrier family 2 member 1 Homo sapiens
2 When complexed with cytosolic ATP, GluT1 exhibits increased affinity for the sugar export site ligand cytochalasin B, prolonged substrate occlusion, reduced net sugar import capacity, and diminished reactivity with carboxyl terminal peptide-directed antibodies. Sugars solute carrier family 2 member 1 Homo sapiens
3 The effects of ATP on GluT1-mediated sugar transport may be determined by the number of ATP molecules complexed with the transporter. Sugars solute carrier family 2 member 1 Homo sapiens