Pub. Date : 2002 Oct
PMID : 12376463
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We have shown that tamoxifen treatment resulted in G(1) arrest in two cell lines, HN5 and HN6. | Tamoxifen | MT-RNR2 like 6 (pseudogene) | Homo sapiens |
| 2 | There was a significant sensitizing effect of tamoxifen on cisplatin-induced apoptosis in HN5 and HN6 cells, with the combined treatment being more effective in inducing apoptosis. | Tamoxifen | MT-RNR2 like 6 (pseudogene) | Homo sapiens |
| 3 | However, tamoxifen treatment resulted in increased secretion of TGF-beta1 by HN5 and HN6 cells. | Tamoxifen | MT-RNR2 like 6 (pseudogene) | Homo sapiens |
| 4 | An anti-TGF-beta blocking antibody prevented both the blockade of cellular proliferation and the increased expression of CDKIs associated with tamoxifen treatment of HN5 and HN6 cells. | Tamoxifen | MT-RNR2 like 6 (pseudogene) | Homo sapiens |