Title : Iron increases expression of iron-export protein MTP1 in lung cells.

Pub. Date : 2002 Nov

PMID : 12376346






7 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Iron increases expression of iron-export protein MTP1 in lung cells. Iron solute carrier family 40 member 1 Homo sapiens
2 Iron increases expression of iron-export protein MTP1 in lung cells. Iron solute carrier family 40 member 1 Homo sapiens
3 We provide evidence for the expression and iron-induced upregulation of the metal transporter protein-1 (MTP1) genes in human and rodent lung cells at both the protein and mRNA levels. Iron solute carrier family 40 member 1 Homo sapiens
4 We provide evidence for the expression and iron-induced upregulation of the metal transporter protein-1 (MTP1) genes in human and rodent lung cells at both the protein and mRNA levels. Iron solute carrier family 40 member 1 Homo sapiens
5 In human bronchial epithelial cells, a 3.8-fold increase in mRNA level and a 2.4-fold increase in protein level of MTP1 were observed after iron exposure. Iron solute carrier family 40 member 1 Homo sapiens
6 In freshly isolated human macrophages, as much as an 18-fold increase in the MTP1 protein level was detected after incubation with an iron compound. Iron solute carrier family 40 member 1 Homo sapiens
7 The elevation in expression of MTP1 gene was also demonstrated in iron-instilled rat lungs and in hypotransferrinemic mouse lungs. Iron solute carrier family 40 member 1 Homo sapiens