Title : The antidepressant tianeptine persistently modulates glutamate receptor currents of the hippocampal CA3 commissural associational synapse in chronically stressed rats.

Pub. Date : 2002 Sep

PMID : 12372016






3 Functional Relationships(s)
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1 The antidepressant tianeptine persistently modulates glutamate receptor currents of the hippocampal CA3 commissural associational synapse in chronically stressed rats. tianeptine carbonic anhydrase 3 Rattus norvegicus
2 Here, the effects of long-term antidepressant application in rats with the drug tianeptine were examined at hippocampal CA3 commissural associational (c/a) glutamate receptor ion channels, employing the whole-cell patch-clamp technique. tianeptine carbonic anhydrase 3 Rattus norvegicus
3 These results indicate that tianeptine targets the phosphorylation-state of glutamate receptors at the CA3 c/a synapse. tianeptine carbonic anhydrase 3 Rattus norvegicus