Title : Adenosine release in nucleus tractus solitarii does not appear to mediate hypoxia-induced respiratory depression in rats.

Pub. Date : 2002 Oct 1

PMID : 12356889






1 Functional Relationships(s)
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1 Addition of the ecto-5"-nucleotidase inhibitor alpha,beta-methylene ADP (200 microM) to the dorsal surface of the brainstem completely abolished the signal evoked by hypoxia, suggesting that the inosine arose from adenosine that was produced in the extracellular space by the prior release of ATP. alpha,beta-methyleneadenosine 5'-diphosphate 5' nucleotidase, ecto Rattus norvegicus