Title : Active-site clashes prevent the human 3-methyladenine DNA glycosylase from improperly removing bases.

Pub. Date : 2002 Sep

PMID : 12323378






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In the crystal structure of AAG bound to DNA containing 1,N(6) ethenoadenine, an asparagine (N169) occupies the active-site floor, in close proximity to the C-2 position of the flipped-out 1,N(6) ethenoadenine. Asparagine N-methylpurine DNA glycosylase Homo sapiens