Pub. Date : 2002 Oct
PMID : 12235264
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Histamine h(4) and h(2) receptors control histamine-induced interleukin-16 release from human CD8(+) T cells. | Histamine | interleukin 16 | Homo sapiens |
| 2 | Histamine is known to trigger the release of interleukin (IL)-16 from human CD8(+) cells. | Histamine | interleukin 16 | Homo sapiens |
| 3 | Histamine stimulation of human CD8(+) T lymphocytes purified from peripheral blood led to a 5- to 8-fold increase in the basal release of IL-16 within 24 h, and this increase was significantly blocked by the H(2)-selective antagonist, cimetidine, or by thioperamide, an antagonist of H(3) and H(4) receptors, respectively. | Histamine | interleukin 16 | Homo sapiens |