Pub. Date : 2002 Aug
PMID : 12228764
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cyclosporin A and FK506 decrease adenosine kinase activity and adenosine uptake in T-lymphocytes. | Tacrolimus | adenosine kinase | Homo sapiens |
| 2 | The immunosuppressive drugs cyclosporin A (CsA) and FK506 inhibited both adenosine uptake and AK activity in a concentration-dependent manner. | Tacrolimus | adenosine kinase | Homo sapiens |
| 3 | These data demonstrate that CsA and FK506 enhance adenosine concentrations in T-lymphocytes by way of a mechanism that involves AK inhibition. | Tacrolimus | adenosine kinase | Homo sapiens |