Title : Defective CD19-dependent signaling in B-1a and B-1b B lymphocyte subpopulations.

Pub. Date : 2002 Sep

PMID : 12213328






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 BCR induced tyrosine phosphorylation of CD19 was transient in B-1 cells while it was prolonged in splenic B-2 cells. Tyrosine membrane spanning 4-domains A1 Homo sapiens
2 However, the tyrosine phosphorylated CD19 in B-1 cells binds less phosphatidylinositol 3-kinase (PI3-K) compared to B-2 cells. Tyrosine membrane spanning 4-domains A1 Homo sapiens