Title : PACAP potentiates L-type calcium channel conductance in suprachiasmatic nucleus neurons by activating the MAPK pathway.

Pub. Date : 2002 Sep

PMID : 12205158






2 Functional Relationships(s)
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1 Down-regulation of protein kinase C (PKC) with the phorbol ester 12-O-tetradecanoyl phorbol 13-acetate (TPA) or PKC inhibition with bisindolylmaleimide attenuated the actions of PACAP, indicating that PKC also couples PACAP to potentiation of depolarization-induced Ca(2+) transients. bisindolylmaleimide proline rich transmembrane protein 2 Homo sapiens
2 Down-regulation of protein kinase C (PKC) with the phorbol ester 12-O-tetradecanoyl phorbol 13-acetate (TPA) or PKC inhibition with bisindolylmaleimide attenuated the actions of PACAP, indicating that PKC also couples PACAP to potentiation of depolarization-induced Ca(2+) transients. bisindolylmaleimide proline rich transmembrane protein 2 Homo sapiens