Title : CD38 expression and NAD+-induced intracellular Ca+ mobilization in isolated retinal Müller cells.

Pub. Date : 2002 Sep

PMID : 12203397






1 Functional Relationships(s)
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1 The cellular mechanism that supports internal mobilization of calcium appears to depend on a complex multifunctional ectoenzyme, CD38, which converts NAD(+) into the intracellular Ca(2+)-mobilizing second-messenger cyclic ADP-ribose (cADPR) and could function as a detector for extracellular NAD(+), thus providing a novel signal detection system for evaluating the extracellular environment. Calcium CD38 molecule Homo sapiens