Title : Mice expressing the human CYP7A1 gene in the mouse CYP7A1 knock-out background lack induction of CYP7A1 expression by cholesterol feeding and have increased hypercholesterolemia when fed a high fat diet.

Pub. Date : 2002 Nov 8

PMID : 12202481






1 Functional Relationships(s)
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Protein Name
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1 A diet containing 1% cholic acid reduced the expression of the human gene in mCYP7A1(-/-)/hCYP7A1 mice to undetectable levels. Cholic Acid cytochrome P450 family 7 subfamily A member 1 Homo sapiens