Title : Initial steps of Shigella infection depend on the cholesterol/sphingolipid raft-mediated CD44-IpaB interaction.

Pub. Date : 2002 Sep 2

PMID : 12198147






2 Functional Relationships(s)
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1 Initial steps of Shigella infection depend on the cholesterol/sphingolipid raft-mediated CD44-IpaB interaction. Sphingolipids CD44 molecule (Indian blood group) Homo sapiens
2 We identified a molecular complex involving proteins of both the host, CD44 the hyaluronan receptor, and Shigella, the invasin IpaB, which partitions during infection within specialized membrane microdomains enriched in cholesterol and sphingolipids, called rafts. Sphingolipids CD44 molecule (Indian blood group) Homo sapiens