Title : Genetically engineered analogs of ascomycin for nerve regeneration.

Pub. Date : 2002 Sep

PMID : 12183690






1 Functional Relationships(s)
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1 The polyketides FK506 (tacrolimus) and FK520 (ascomycin) are potent immunosuppressants that function by inhibiting calcineurin phosphatase through formation of an FKBP12-FK506/520-calcineurin ternary complex. Polyketides FKBP prolyl isomerase 1A Rattus norvegicus