Pub. Date : 2002 Aug
PMID : 12171167
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: Addition of reIL-1beta increased the expression of COX-2 in a dose-dependent manner, which was paralleled by an increased concentration of PGE2 in culture medium. | Dinoprostone | cytochrome c oxidase subunit II | Equus caballus |
| 2 | CONCLUSIONS AND CLINICAL RELEVANCE: Prostaglandin E2 is considered to be an important mediator in the pathophysiologic processes of arthritis, and cultured chondrocytes respond to interleukin-1 with enhanced expression and activity of COX-2. | Dinoprostone | cytochrome c oxidase subunit II | Equus caballus |