Title : Monoamine-dependent production of reactive oxygen species catalyzed by pseudoperoxidase activity of human hemoglobin.

Pub. Date : 2002 Jun

PMID : 12162542






1 Functional Relationships(s)
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1 We propose that the O2*- generation and Asc* formation in the Hb solution are due to the pseudoperoxidase activity-dependent oxidation of PEA and resultant ROS may damage tissues rich in monoamines, if the Hb-based blood substitutes were circulated without addition of ROS scavengers such as thiols. monoamines PYD and CARD domain containing Homo sapiens