Title : Duration of calcineurin and Erk signals regulates CD4/CD8 lineage commitment of thymocytes.

Pub. Date : 2002 Jan

PMID : 12142035






1 Functional Relationships(s)
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1 The calcineurin inhibitor FK506 at 1nM inhibited the development of thymocytes to either lineage, but 0.3nM FK506 significantly switched the development from the CD4 cell fate to the CD8 cell fate. Tacrolimus CD8a molecule Homo sapiens