Pub. Date : 2002
PMID : 12138244
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | RNase protection assay showed a negative correlation between bcl-x(L) and mcl-1 mRNA expression levels and the sensitivity to 5-FU and gemcitabine after 5-FU and gemcitabine treatment. | Fluorouracil | BCL2 like 1 | Homo sapiens |
2 | RNase protection assay showed a negative correlation between bcl-x(L) and mcl-1 mRNA expression levels and the sensitivity to 5-FU and gemcitabine after 5-FU and gemcitabine treatment. | Fluorouracil | BCL2 like 1 | Homo sapiens |
3 | The bax/bcl-2 ratio is predictive of chemotherapy sensitivity, whereas bcl-x(L) and mcl-1 mRNA levels following repeated exposure to 5-FU or gemcitabine are associated with resistance to these drugs. | Fluorouracil | BCL2 like 1 | Homo sapiens |