Title : Iron-sulfur cluster biosynthesis: characterization of iron nucleation sites for assembly of the [2Fe-2S]2+ cluster core in IscU proteins.

Pub. Date : 2002 Jul 31

PMID : 12137512






8 Functional Relationships(s)
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1 Iron-sulfur cluster biosynthesis: characterization of iron nucleation sites for assembly of the [2Fe-2S]2+ cluster core in IscU proteins. Iron iron-sulfur cluster assembly enzyme Homo sapiens
2 Iron-sulfur cluster biosynthesis: characterization of iron nucleation sites for assembly of the [2Fe-2S]2+ cluster core in IscU proteins. Iron iron-sulfur cluster assembly enzyme Homo sapiens
3 The intermediate [2Fe-2S] IscU-bound cluster is formed by delivery of iron and sulfur to the apo-IscU, with the latter delivered through an IscS-mediated reaction. Iron iron-sulfur cluster assembly enzyme Homo sapiens
4 The intermediate [2Fe-2S] IscU-bound cluster is formed by delivery of iron and sulfur to the apo-IscU, with the latter delivered through an IscS-mediated reaction. Iron iron-sulfur cluster assembly enzyme Homo sapiens
5 In this report we characterize iron-binding sites on IscU that appear to nucleate [2Fe-2S] cluster assembly. Iron iron-sulfur cluster assembly enzyme Homo sapiens
6 This iron-bound form of IscU is shown to be viable for subsequent IscS-mediated assembly of holo-IscU. Iron iron-sulfur cluster assembly enzyme Homo sapiens
7 This iron-bound form of IscU is shown to be viable for subsequent IscS-mediated assembly of holo-IscU. Iron iron-sulfur cluster assembly enzyme Homo sapiens
8 The latter observation reflects the low binding affinity of persulfido IscU for iron ion. Iron iron-sulfur cluster assembly enzyme Homo sapiens