Title : Glycogen synthase kinase 3beta is activated by cAMP and plays an active role in the regulation of melanogenesis.

Pub. Date : 2002 Sep 13

PMID : 12093801






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In this report, we showed that cAMP, through a protein kinase A-independent mechanism, led to inhibition of AKT phosphorylation and activity. Cyclic AMP AKT serine/threonine kinase 1 Homo sapiens
2 Consistent with the role of AKT in the regulation of glycogen synthase kinase 3beta (GSK3beta), cAMP decreased the phosphorylation of GSK3beta and stimulated its activity. Cyclic AMP AKT serine/threonine kinase 1 Homo sapiens