Title : Interactions of fluorochemicals with rat liver fatty acid-binding protein.

Pub. Date : 2002 Jul 15

PMID : 12093614






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The hypothesis that perfluorooctanesulfonate (PFOS), perfluorooctanoate (PFOA), and certain related perfluorooctanesulfonamide-based fluorochemicals (PFOSAs) can interfere with the binding affinity of L-FABP for fatty acids was tested. perfluorooctane sulfonic acid fatty acid binding protein 1 Rattus norvegicus
2 PFOS exhibited the highest level of inhibition of DAUDA-L-FABP binding in the competitive binding assays, followed by N-EtFOSA, WY, and, with equal IC(50)s, N-EtFOSE and PFOA. perfluorooctane sulfonic acid fatty acid binding protein 1 Rattus norvegicus