Pub. Date : 2002 Jul 15
PMID : 12083801
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Superoxide anion-dependent Raf/MEK/ERK activation by peroxisome proliferator activated receptor gamma agonists 15-deoxy-delta(12,14)-prostaglandin J(2), ciglitazone, and GW1929. | Superoxides | zinc fingers and homeoboxes 2 | Homo sapiens |
| 2 | In this study, we for the first time demonstrate a novel mechanism, independent of Ras activation but initiated by superoxide anion production, for PPARgamma agonists to trigger the Raf-MEK-ERK1/2 signaling pathway. | Superoxides | zinc fingers and homeoboxes 2 | Homo sapiens |