Title : Absence of platelet endothelial cell adhesion molecule-1 (CD31) leads to increased severity of local and systemic IgE-mediated anaphylaxis and modulation of mast cell activation.

Pub. Date : 2002 Jun 15

PMID : 12055265






1 Functional Relationships(s)
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1 PECAM-1(-/-) mice exhibited elevated serum histamine concentrations after Ag stimulation compared with PECAM-1(+/+) mice, indicating an increased severity of systemic IgE-mediated anaphylaxis. Histamine platelet/endothelial cell adhesion molecule 1 Mus musculus