Pub. Date : 2002 Apr 26
PMID : 12051861
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The C-terminal extension of the small GTPase Ran is essential for defining the GDP-bound form. | Guanosine Diphosphate | ran GTP-binding protein | Xenopus laevis |
| 2 | Here, we show that a deletion mutant of Ran, lacking the entire C-terminal extension, termed Ran Core, can bind to importin beta in its GDP-bound form with high affinity. | Guanosine Diphosphate | ran GTP-binding protein | Xenopus laevis |
| 3 | Here, we show that a deletion mutant of Ran, lacking the entire C-terminal extension, termed Ran Core, can bind to importin beta in its GDP-bound form with high affinity. | Guanosine Diphosphate | ran GTP-binding protein | Xenopus laevis |
| 4 | Our results demonstrate that the C terminus of Ran is a major determinant of the state of Ran, and that removal of this allows the GDP-bound form to adopt a GTP-like conformation, thereby creating a constitutively active protein. | Guanosine Diphosphate | ran GTP-binding protein | Xenopus laevis |
| 5 | Our results demonstrate that the C terminus of Ran is a major determinant of the state of Ran, and that removal of this allows the GDP-bound form to adopt a GTP-like conformation, thereby creating a constitutively active protein. | Guanosine Diphosphate | ran GTP-binding protein | Xenopus laevis |