Title : Tonin expression in the rat brain and tonin-mediated central production of angiotensin II.

Pub. Date : 2002 Jun 1

PMID : 12044607






2 Functional Relationships(s)
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1 Central microinjection of tonin produced a transient (10-20 min) elevation of blood pressure and heart rate and induced water and saline intake within the first 10 min after injection. Water kallikrein 1-related peptidase C2 Rattus norvegicus
2 Our data suggest that tonin may be an alternative pathway to Ang II generation in the brain and could participate in the physiological effects exerted by Ang II such as water and saline intake and blood pressure elevation. Water kallikrein 1-related peptidase C2 Rattus norvegicus