Title : Effect of rapamycin on the cyclosporin A-resistant CD28-mediated costimulatory pathway.

Pub. Date : 2002 Jun 15

PMID : 12036883






1 Functional Relationships(s)
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1 Treatment with rapamycin blocked IL-2 production after activation of human peripheral blood T cells with phorbol ester (PMA) and anti-CD28 (CsA-resistant pathway), whereas this drug did not have any effect on PMA plus ionomycin stimulation (CsA-sensitive pathway). Sirolimus interleukin 2 Homo sapiens