Title : IL-1beta expression in islet cells of the NOD mouse and its spatial relationship to beta cells and inducible nitric oxide synthase.

Pub. Date : 2002 Apr

PMID : 12021104






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The expression of IL-1beta in the NOD mouse pancreas was examined following disease acceleration with cyclophosphamide (Cy). Cyclophosphamide interleukin 1 beta Mus musculus
2 The expression of IL-1beta in the NOD mouse pancreas was examined following disease acceleration with cyclophosphamide (Cy). Cyclophosphamide interleukin 1 beta Mus musculus
3 At day 0 (Cy group), IL-1beta was expressed in selective intraislet macrophages but showed an increase from day 7 onwards in macrophages, a few beta cells, and somatostatin cells. Cyclophosphamide interleukin 1 beta Mus musculus
4 In the Cy group a proportion of macrophages coexpressed IL-1beta and inducible nitric oxide synthase (iNOS). Cyclophosphamide interleukin 1 beta Mus musculus