Title : Endothelial nitric oxide synthase and its negative regulator caveolin-1 localize to distinct perinuclear organelles.

Pub. Date : 2002 Jun

PMID : 12019294






2 Functional Relationships(s)
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Protein Name
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1 On treatment of the cells with the microtubule-depolymerizing drug nocodazole, the Golgi complex is scattered and caveolin-1 is found in vesicles at the periphery of the cell, while eNOS is localized at large structures near the nucleus. Nocodazole caveolin 1 Bos taurus
2 The localization of eNOS and caveolin-1 at distinct perinuclear compartments that behave differently in the presence of nocodazole indicates that eNOS activity is not regulated by caveolin-1 in the Golgi complex. Nocodazole caveolin 1 Bos taurus