Title : Carvedilol attenuates neuroleptic-induced orofacial dyskinesia: possible antioxidant mechanisms.

Pub. Date : 2002 May

PMID : 12010767






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Chronic haloperidol or chlorpromazine but not clozapine treated rats showed decreased forebrain levels of antioxidant defence enzymes, superoxide dismutase (SOD) and catalase. Chlorpromazine catalase Rattus norvegicus
2 Co-administration of carvedilol (1-2 mg kg(-1)) significantly reversed the haloperidol or chlorpromazine-induced decrease in forebrain SOD and catalase levels in rats. Chlorpromazine catalase Rattus norvegicus