Pub. Date : 2002 May
PMID : 12004990
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | During epinephrine infusion, every LQT1 patient manifested prolongation of the QT interval (paradoxical response), whereas healthy controls and patients with either LQT2 or LQT3 tended to have shortened QT intervals (P<.001). | Epinephrine | potassium voltage-gated channel subfamily Q member 1 | Homo sapiens |
| 2 | Low-dose epinephrine (0.05 microg x kg(-1) x min(-1)) completely discriminated LQT1 patients (AQT, +82+/-34 ms) from controls (AQT, -7+/-13 ms; P<.001). | Epinephrine | potassium voltage-gated channel subfamily Q member 1 | Homo sapiens |
| 3 | CONCLUSIONS: Epinephrine-induced prolongation of the QT interval appears pathognomonic for LQT1. | Epinephrine | potassium voltage-gated channel subfamily Q member 1 | Homo sapiens |
| 4 | Low-dose epinephrine infusion distinguishes controls from patients with concealed LQT1 manifesting an equivocal QTc at rest. | Epinephrine | potassium voltage-gated channel subfamily Q member 1 | Homo sapiens |