Title : Reciprocal mutations of neuropeptide Y receptor Y2 in human and chicken identify amino acids important for antagonist binding.

Pub. Date : 2002 May 8

PMID : 11997008






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Reciprocal mutagenesis between hY2 and chY2 revealed that three of these, individually and in combination, are important for BIIE0246 binding, namely positions Gln(135) in transmembrane (TM) 3, Leu(227) in TM5, and Leu(284) in TM6. BIIE 0246 tropomyosin 3 Homo sapiens