Title : Structural determinants for GoLoco-induced inhibition of nucleotide release by Galpha subunits.

Pub. Date : 2002 Apr 25

PMID : 11976690






1 Functional Relationships(s)
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1 Here we describe the structural determinants of GoLoco activity as revealed by the crystal structure of Galpha(i1) GDP bound to the GoLoco region of the "regulator of G-protein signalling" protein RGS14. Guanosine Diphosphate protein phosphatase 1 regulatory inhibitor subunit 1A Homo sapiens